Licochalcone a CAS 58749-22-7 Skincare Antioxidant From Plant

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Product Description

Basic Info
Model NO.DPE104
EINECS635-513-3
GradePure Essential Oil Grade A
FunctionDermal System
CertificationMSDS
UsageCosmetic Raw Materials
Raw MaterialAgricultural and Sideline Products
Transport MachineOrdinary Goods Truck
Shelf Life2 Years
Purity70%
ApplicationCosmetic
StorageCool Dry Place
QualityRefined
Test MethodHPLC
Sample OrderAccepted
Cro ServiceAccepted
MSDSAvailable
COAAvailable
Transport PackageAluminum Foil Bag
Specification1g; 10g; 500g; 1kg
OriginChina
HS Code29061990
Production Capacity100kg
Product Description
Licochalcone a CAS 58749-22-7 Skincare Antioxidant From Plant
Abstract
Licochalcone A is a potent, natural flavonoid compound derived from the roots of Chinese licorice (Glycyrrhiza inflata), commonly known for its significant anti-inflammatory, antioxidant, antimicrobial, and antitumor effects. It is widely used in dermatology for treating acne, rosacea, and dermatitis, and shows potential as a neuroprotective and anti-obesity agent.
📋 Description
Source: Extracted from Glycyrrhiza inflata and G. glabra (licorice) roots.
Structure: It is an oxygenated chalconoid (C21H22O4).
Appearance: Yellow, crystalline powder with antimicrobial activities against spore-forming bacteria (MIC = 2-15 μg/mL).
⚙️ Function
Anti-inflammatory: Inhibits key pathways such as NF-κB, NLRP3 inflammasome, and reduces inflammatory mediators (IFN-γ, TNF-α, NO).
Antioxidant: Protects skin cells against reactive oxygen species (ROS), lipid peroxidation, and environmental stress (e.g., UV and blue light).
Antitumor/Anticancer: Induces apoptosis (programmed cell death) and inhibits the proliferation, migration, and invasion of various cancer cells, including breast, hepatocellular, and oral squamous cell carcinomas.
Antibacterial/Anti-parasitic: Exhibits strong antibacterial properties (MIC = 2–15 μg/mL) and anti-parasitic action.
💡 Application
🌿Dermatology and Cosmetics: Used to treat acne-prone skin, atopic dermatitis, and rosacea due to its ability to reduce inflammation, redness, and improve the skin barrier.
🌿Skin Care: Used in products to protect against sun damage and premature skin aging.
🌿Pharmacology Research: Studied as a potential therapeutic agent for Alzheimer's disease (due to anti-microglial activation and neuroprotective effects) and metabolic syndromes (e.g., fatty liver).
🌿Key Mechanisms: Licochalcone A modulates multiple signaling pathways including Nrf2/HO-1 for antioxidant defense and PI3K/Akt/mTOR for tumor suppression.
Specification
Item Specification
Color Yellow-brown Powder
Purity 70%
Heavy Metal Complied
Bacteria Count Complied
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Sample Provided

🛡️

Quality Assured

Short-term Delivery

Company Profile

We focus on cosmetic active ingredients, bioactive materials, and plant extract active ingredients. In cosmetics, we develop high-purity, high-stability and skin-friendly active ingredients with anti-aging, moisturizing, repairing and brightening effects through biosynthesis, meeting the demand for natural and efficient raw materials in the global beauty industry. In bioactive raw materials, we provide safe and stable products for functional food, health care and biomedical fields. In plant extract active ingredients, we strictly develop and produce high-quality plant extracts, supporting extract R&D and human health.

In addition, we have strong capabilities in customized peptide synthesis. We have a professional R&D team and an advanced synthesis platform, providing one-stop customized services covering linear peptides, complex cyclic peptides, peptide encapsulation and modification.

Skincare Antioxidant Production Facility
Laboratory R&D Center
Production Control Lab
Packaging & Shipping
Standard Safe Packaging Box
Bottle Packaging Standard
After Sales Service
Customer satisfaction is our pursuit. While ensuring product quality, we make every effort to deliver quickly and meet other customer requirements. If you are interested in the product, please do not hesitate to contact us. We have a complete industry chain and will provide you with free consulting services.
Frequently Asked Questions
Q1: Can you provide samples?
A: Yes! It is available, you can contact our sales team to request sample products.
Q2: What is your MOQ (Minimum Order Quantity)?
A: For most products, there is no minimum requirement. For customized products, we will analyze and evaluate requirements on a case-by-case basis.
Q3: How do you confirm product quality before placing an order?
A: The batch COA (Certificate of Analysis) report will be provided prior to shipping, and pre-shipment samples are also available for inspection.
Q4: What is the estimated delivery time?
A: Generally, for small orders, it takes 5-7 days after order confirmation and payment. Larger bulk orders require approximately 15 days.
Q5: What kind of payment terms do you accept?
A: We accept Swift Wire, LC, Paypal, and Western Union payments.
Q6: Is it possible to use my appointed label or packaging?
A: Yes, OEM packaging and custom labeling services are available to help expand your brand visibility.

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