1. Basic Information

• Chemical Name: D-Panthenol (Provitamin B5)
• Systematic Name: (R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
• Other Common Names: Dextropanthenol; Pantothenol; D-Pantothenyl alcohol
• CAS Registry Number: 81-13-0
• Molecular Weight: 205.25 g/mol

2. Key Characteristics

• Appearance: Colorless to slightly yellowish, viscous, hygroscopic liquid at room temperature.
• Odor: Characteristic, mild odor.
• Solubility: Highly soluble in water, ethanol, methanol, and propylene glycol. Slightly soluble in ether and chloroform.
• Stability: Stable under normal conditions but may darken upon prolonged exposure to light or heat.
• Core Function: It is the alcohol analog of pantothenic acid (Vitamin B5). In living systems, it is readily oxidized in vivo to become active Vitamin B5, a crucial component of coenzyme A.

D-Panthenol is a multifunctional active ingredient prized for its exceptional moisturizing, soothing, and skin/hair conditioning properties.

Personal Care & Cosmetics (Primary Use):

• Intense Moisturizer/Humectant: Penetrates the skin and hair, attracting and binding water, providing deep hydration and improving elasticity.
• Skin Barrier Repair & Soothing Agent: Promotes epidermal regeneration, soothes irritation, and relieves itching. Widely used in products for sensitive skin, after-sun care, diaper rash creams, and wound healing ointments.
• Hair Conditioning & Strengthening: Penetrates the hair shaft, improving moisture content, elasticity, and shine. Reduces breakage and static, making it a key ingredient in shampoos, conditioners, and hair repair treatments.
• Nail Care: Strengthens brittle nails and improves cuticle health.

Topical Preparations:

• Used in ointments, creams, and sprays for minor burns, sunburns, skin abrasions, and post-operative wound care.

Eye & Nasal Care:

• Found in lubricating eye drops and nasal sprays for its protective and moisturizing effects on mucous membranes.

Animal Care:

• Used in veterinary topical products for wound healing and skin conditioning.